It argues that having low levels of endocannabinoids can negatively affect many different areas of the body, causing several chronic health issues. These research findings reinforce the vital role that this system plays to regulate areas of human physiology. CB2 receptors are especially associated with an inflammatory response. When these receptors are activated, they stimulate a response that minimizes damage to tissues and can reduce pain.
CB1 receptors can be found primarily in the brain and throughout the central nervous system. CB2 receptors are primarily present in the immune system, organs, and tissues. CB2 receptors do have a small presence in the brain, but they are far outweighed by the presence of CB1 receptors.
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The ECS consists of neurotransmitters , receptors, and enzymes . The two different types of receptors in this system are called CB1 and CB2 receptors.
A 2006 study found that stimulating CB2 receptors can help reduce pain and allow the body to repair itself. These anti-inflammatory and analgesic effects of CB2 agonists may be beneficial for patients living with inflammation-related disorders, like gastrointestinal conditions. CB2 receptors are found in the immune system and peripheral nervous system.
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Because they are located in our body’s periphery, the activation of CB2 receptors doesn’t result in psychotropic effects. CB1 receptors are located primarily in the brain and central nervous system. They are also present in the kidneys, liver, lungs and reproductive organs. The activation of CB1 receptors has cerebral and behavioral effects.
When threats to your biological balance emerge, signaling molecules called cannabinoids, or eCBs, bind to these receptors to trigger cascades of homeostasis throughout the body. This study links to a theory known in scientific communities as clinical endocannabinoid deficiency .
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You can boost the ECS through specific changes to your diet, regular exercise, and the consumption of cannabinoids. The consumption of exogenous cannabinoids, such as CBD, is a step that you can take to stimulate the endocannabinoid system. CB1 and CB2 receptors both play very different roles in the body.